3D Cell Culture Tools

3D cell culture simulates the in-vivo like growth environment, promoting expansion of cells while greatly reducing loss of phenotype, compared to traditional plastic flat surface 2D cell culture.




 

 

Biotechnology products for cellular biomechanics 
Apply tension, shear stress, or compression to cells in 2D and 3D culture with Flexcell® International products.
http://www.flexcellint.com/index.html

image

 

Flexcell® CULTURE SYSTEMS & TISSUE ENGINEERING
Flexcell® manufactures devices for applying tension, compression, and fluid shear to cells in
2D and 3D culture and microscopy devices for viewing real-time responses to mechanical load.
3D cell culture in a gel matrix to create linear, trapezoidal and circular 3D tissue constructs.

Microscopy Devices
View cells undergoing tension, compression and fluid shear in real time.
Fluid Flow Stress
Apply fluid shear stress to cell cultures or watch them in real time with Flexcell shear stress devices.
Flexcell Culture Plates
A unique range of culture plates provide matrix bonded growth surfaces to promote attachment of a wide range of cell types.

Culturing Cells in a Mechanically Active Environment:
Cell Stretching and Tissue Engineering
Flexcell®  specializes in designing and manufacturing products to stretch cells in culture. Our products allow you to apply mechanical loads (i.e., tensioncompression, and fluid flow) to cells in monolayer and 3D culture. Flexcell® products are used for applications including tissue engineering, drug discovery, cytomechanics, orthopaedics, cardiovascular, and pulmonary research, to name a few.

Flexcell® Tension Systems


FX-5000 Tension

Flexcell® FX-5000™ Tension System 
A computer-regulated bioreactor that uses vacuum pressure to apply cyclic or static strain to cells cultured on flexible-bottomed culture plates.

Learn more...

Flex Jr.

Flexcell® Flex Jr.™ Tension System 
A computer-regulated bioreactor that uses vacuum pressure to apply cyclic or static strain to cells in microscope devices.

Learn more...

StageFlexer

Flexcell® StageFlexer® (Microscopy) 
A single-well embodiment of the BioFlex® culture plate designed to allow the user to observe signaling responses to strain in real time on a microscope stage.

Learn more...

StageFlexer Jr.

Flexcell® StageFlexer® Jr. (Microscopy) 
A compact strain device designed to accept membranes removed from the well of a BioFlex®, Tissue Train®, or UniFlex® culture plate and observe signaling responses to strain in real time.

Learn more...

Tension FlexLink

Flexcell® FX5K™ Tension FlexLink® 
A remote tension unit that works in conjunction with the FX-5000™ Tension System allowing the user to simultaneously run two different regimens on two different baseplates.

Learn more...

BioFlex

BioFlex® Culture Plates 
Flexible-bottomed culture plate that works with the FX-5000™ Tension System to provide a mechanical load regimen to your cells.

Learn more...

UniFlex

UniFlex® Culture Plate 
Flexible-bottomed culture plate that works with the FX-5000™ Tension System to provide uniaxial strain to cells in monolayer culture. 

Learn more...

Flexcell® Compression Systems 


FX-5000 Compression

Flexcell® FX-5000™ Compression System 
A computer-regulated bioreactor that uses positive air pressure to deform tissue samples or 3D cell cultures in vitro, simulating biological compression conditions.

Learn more...

StagePresser

Flexcell® StagePresser™ (Microscopy) 
A single-well embodiment of the compression apparatus designed to allow the user to detect signaling responses to compression in real time.

Learn more...

Compression FlexLink

Flexcell® FX5K™ Compression FlexLink® 
A remote compression unit that works in conjunction with the FX-5000™ Compression System allowing the user to simultaneously run two different regimens on two different baseplates.

Learn more...

BioPress

BioPress™ Compression Plates 
Works with the FX-5000™ Compression System to simulate biological compression conditions using pressure to deform tissue samples or cells cultured in a matrix.

Learn more...

StagePresserMembrane

StagePresser™ Membranes 
Flexible growth surfaces that are individually packaged free membranes for the StagePresser™ dynamic culture product.

Learn more...

Tissue Train® Tension System
Apply Strain to Cells in 3D Gel Culture Flexcell®                            


Tissue Train

Flexcell® Tissue Train® Culture System 
A computer-regulated bioreactor that allows users to create 3-dimensional cell-seeded gels and apply uniaxial tensile strains to these gels.

Learn more...

StageFlexer Jr.

Flexcell® StageFlexer® Jr. (Microscopy) 
A compact strain device designed to accept membranes removed from the well of a BioFlex®, Tissue Train®, or UniFlex® culture plate and observe signaling responses to strain in real time.

Learn more...

Tissue Train Plate

Tissue Train® Culture Plate
with nylon mesh or NEW foam anchor tabs 
Works with the Tissue Train® System to create linear, tethered 3D cell-seeded gel constructs and to provide uniaxial cyclic strain to cells in a gel matrix.

Learn more...

Tissue Train Plate

Trapezoidal Tissue Train® Culture Plate
with nylon mesh or NEW foam anchor tabs 
Works with the Tissue Train® System to create 3D trapezoidal-shaped bioartificial tissue constructs.

Learn more...

Tissue Train Plate

Tissue Train® Circular Foam Culture Plate 
Works with the Tissue Train® System to create circular 3D cell-seeded gel constructs and to provide biaxial cyclic strain to cells in a gel matrix.

Learn more...

ScanFlex

Flexcell® ScanFlex™ with XyFlex™ 
An automated scanning device with area measurement software.

Learn more...

 

HiQ Flowmate

Flexcell® HiQ Flowmate® Fluid Control System 
A dual syringe pump for macro, micro, and nanofluidic applications.

Learn more...