Novel bio-competent bio-reagents for your cell culture research.

PhenoDrive allows you to control the phenotype of your cells as in their natural micro-environment.

PhenoDrives are a range of fully synthetic, biomimetic materials to provide simple, single step solutions to control your cell culture models and preserve phenotype through mimicry of the extra cellular matrix.

PhenoDrive has been successfully used in both single and co-cultures of a range of cells.

Each PhenoDrive product has been specifically designed to either mimic a separate component of the extra cellular matrix essential for appropriate cell phenotype and function, or to manipulate the cells surrounding milieu to provide an environment that mimics that seen in vivo.

The unique, bespoke design of each PhenoDrive allows the presentation of its bio-cue to the cells to ensure maximum in vivo effect.

Ensuring the preservation of cells

PhenoDrive ensures the preservation of your cells original phenotype, facilitates cell sprouting and their organisation into organoid structures, similar to those seen in vivo.

The products in the PhenoDrive family are specifically tailored to your cell type, in order to understand which PhenoDrive is appropriate for your cells and application we recommend contacting us.

Novel bio-competent bio-reagents for your cell culture research.

PhenoDrive allows you to control the phenotype of your cells as in their natural micro-environment.

PhenoDrives are a range of fully synthetic, biomimetic materials to provide simple, single step solutions to control your cell culture models and preserve phenotype through mimicry of the extra cellular matrix.

PhenoDrive has been successfully used in both single and co-cultures of a range of cells.

Each PhenoDrive product has been specifically designed to either mimic a separate component of the extra cellular matrix essential for appropriate cell phenotype and function, or to manipulate the cells surrounding milieu to provide an environment that mimics that seen in vivo.

The unique, bespoke design of each PhenoDrive allows the presentation of its bio-cue to the cells to ensure maximum in vivo effect.

Ensuring the preservation of cells

PhenoDrive ensures the preservation of your cells original phenotype, facilitates cell sprouting and their organisation into organoid structures, similar to those seen in vivo.

The products in the PhenoDrive family are specifically tailored to your cell type, in order to understand which PhenoDrive is appropriate for your cells and application we recommend contacting us.

Novel bio-competent bio-reagents for your cell culture research.

PhenoDrive allows you to control the phenotype of your cells as in their natural micro-environment.

PhenoDrives are a range of fully synthetic, biomimetic materials to provide simple, single step solutions to control your cell culture models and preserve phenotype through mimicry of the extra cellular matrix.

PhenoDrive has been successfully used in both single and co-cultures of a range of cells.

Each PhenoDrive product has been specifically designed to either mimic a separate component of the extra cellular matrix essential for appropriate cell phenotype and function, or to manipulate the cells surrounding milieu to provide an environment that mimics that seen in vivo.

The unique, bespoke design of each PhenoDrive allows the presentation of its bio-cue to the cells to ensure maximum in vivo effect.

Ensuring the preservation of cells

PhenoDrive ensures the preservation of your cells original phenotype, facilitates cell sprouting and their organisation into organoid structures, similar to those seen in vivo.

The products in the PhenoDrive family are specifically tailored to your cell type, in order to understand which PhenoDrive is appropriate for your cells and application we recommend contacting us.

Cell Stretching Bioreactors for Life Science Research

Tension Systems

Flexcell® Tension Systems are patented, computer-regulated bioreactors that apply cyclic or static strain to cells cultured in vitro. We designed Flexcell® Tension Systems to help investigators analyze biochemical changes in response to tensile load on a variety of cell culture applications, including muscle, lung, heart, vascular vessels, skin, tendon, ligament, cartilage, and bone. Our Tension Systems work with UniFlex® (Uniaxial strain) and/or BioFlex® (Equibiaxial strain) culture plates.

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Compression Systems

Flexcell’s® Compression System regulates positive air pressure to compress tissue samples or 3D cell cultures in vitro. The FX-5000C™ Compression System compresses samples between a piston and stationary platen using our BioPress™ culture plates. It can load up to 14 lbs. of applied force. Using the FX-5000C™ Compression System, researchers can observe biochemical changes and cell signaling in vitro that mimics in vivo conditions.

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Fluid Shear Systems

The Streamer® is a fluid shear stress device allowing users to regulate fluid shear stress to cells in culture with laminar, pulsatile, or oscillating flow. Flexcell’s® Streamer® System uses a computer-controlled peristaltic pump. Together with the Osci-Flow® Flow Controller, researchers can regulate the frequency of oscillation or pulsatile patterns based on shear stress level applied from 0-35 dynes/cm2. Flexcell’s® Fluid Shear System is designed to allow users to observe biochemical changes, cell migration and signaling under fluid shear load in vitro.

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Our ScreenFect® transfection reagents are developed using patented combinatorial chemistry methods, which generates chemical libraries. Using these chemical libraries, candidate reagents are identified by high-throughput cell screening approaches. High performing reagents are further optimized for specific applications.

Our ScreenFect® transfection reagents can be used for transfection of nucleic acid molecules (pDNA, siRNA, mRNA, miRNA) as well as co-transfection of combinations of these. 

ScreenFect® reagents provide excellent performance in many standard cell lines as well as difficult-to-transfect primary and stem cells.

Examples of cell lines successfully transfected with ScreenFect® reagents can be found here. 

Our ScreenFect® transfection reagents have these performance qualities:

✚ Very high transfection efficiency
✚ Low cytotoxity
✚ Serum compatible and no need to change media
✚ Free of animal derived components
✚ Perfect for high throughput screenings
✚ Perfect for large scale transfection

IVTech’s new LiveBox system is the Next Generation of in-vitro models.

Multi-Organ environment simulation is the great advantage.

The beauty of the LiveBox system is its physiological 3D cell culture environment.

It simulates interaction between human organs in a multi organ environment.  Physiological 3D cell culturing makes for a dynamic cell culture.

The LiveBox bioreactors are based on standard 12 or 24 well plate dimensions and offer possibilities for real time monitoring.

A physiologically 3D dynamic culture has been shown to be more sensitive than in a static cell culture. They are also more resistant to drug candidates than a 2D cell culture.

Down regulation of anti-apoptotic features have been observed in physiologically 3D dynamic cultures.

LiveBox systems have been shown to provide a closer prediction of in-vivo drug efficacy than a 2D static model.

The modularity of the IVTech LiveBox culture systems allows greater accuracy in the study of complex tissue responses such as inflammation and cancer.

LVL technologies manufactures 2D datamatrix tubes for sample management of high sample throughput (e.g. bio banks ). LVL technologies has developed a unique data matrix tube rack system by making use of the latest technologies and made in the EU by modern injection molding machines, tools and lasers.

FIVEphoton Biochemicals

FIVEphoton Biochemicals, a domestic and international supplier, provides high quality, reliable and validated research kits and reagents to scientists in life science corporations and academic laboratories to excel in their experimentation.

FD NeuroTechnologies, Inc.

FD NeuroTechnologies, Inc. is a unique biotechnology company dedicated to the morphological studies of the central nervous system. Established in 1996, their products and services have been utilized internationally. They are highly regarded experts in the fields of neurohistology, neurohistopathology, and immunohistochemistry, with hundreds of citations in peer-review journals. Their most widely cited staining kits include FD Rapid GolgiStain Kit, FD MultiStain Kit, FD NeuroApop Kit, and FD NeuroSilver Kit II.

pluriMate

pluriMate is a new PBMC isolation aid for perfect blood overlay every time.  pluriMate dramatically assists the researcher in obtaining quick, consistent results.

pluriMate® was developed for optimal separation of leukocytes and peripheral blood mononuclear cells (PBMC) from whole blood and bone marrow. The key feature of pluriMate® is the porous sponge incorporated at the bottom of the centrifuge tube. This barrier consists of high-grade polyurethane. It prevents you from time-consuming and laborious overlaying of the sample material. Anticoagulated blood or bone marrow can simply be poured directly from the blood sampling tube into the pluriMate® tube. The porous barrier prevents mixture of the sample material with the separation medium. During centrifugation, leucocytes, lymphocytes and PBMCs are separated from unwanted erythrocytes and granulocytes, depending on the density gradient used (Leuko Spin, Lympho Spin, PLT Spin etc.) on the basis of their density and enriched in an interphase above the separation medium. When separation is complete, the barrier prevents recontamination of the enriched cell fraction during harvest. Regardless of whether large or small sample volumes are to be processed.

Biotech Support Group

Biomarker discovery for personalized heath care monitoring in the future. 
Biotech Support Group creates new methods and applications to drive better data quality and efficient workflows for all proteomic and biomarker analyses.

ProteoChem

ProteoChem manufactures analytical standards for NMR and mass spectrometry, protein crosslinkers, and novel proteomics reagents for protein detection and protein modification used in mass spectrometry, drug development, diagnostics, and protein biology.